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In the present study rapid melt tablets (RMT's) of carvedilol were prepared by using ionotropic-gelated chitosan nanoparticles using a spray-drying method. Carvedilol is beta-adrenergic antagonist and its oral bioavailability is about 25-35% because of first pass metabolism.

Nano and Microparticulate Chitosan Based System for Formulation of Carvedilol Rapid Melt Tablet