English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

In this research work, bicomponent structures of salicylic acid were synthesized by reflux condition. The cofomers used were 1-10-phenanthroline, 5-chlorobenzotiazole, and 2-amino-5-methylpyridine. The yield of resultant crystals was calculated at about 60–70 %. It was concluded that bicomponent polymorphs  1–3  were formed by treating salicylic acid (SA) with 10-phenathroline (1-10-Phen), 5-chlorobenzotiazole (5-ClB), and 2-amino-5-methylpyridine (2A-5M-P) respectively. The intermolecular interactions were further confirmed by their computational studies. Molecular docking revealed that the binding nature of salicylic acid can be tuned upon cocrystallization or molecular salt formulation. Antioxidant and antibacterial activities (against Gram-positive and Gram-negative bacteria) were also performed in this study. The MP, and FT-IR, were used for the structure elucidation.

Bicomponent polymorphs of salicylic acid, their antibacterial potentials, intermolecular interactions, DFT and docking studies