English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The kinetics and mechanism of manganese(II) catalyzed oxidation of atenolol by cerium(IV) sulfate in aqueous H 2 SO 4  at a constant ionic strength of 0.50 mol dm -3  was studied spectrophotometrically. The reaction showed first order kinetics in cerium(IV) whereas fractional order in both manganese(II) and atenolol. Addition of products showed no effect on the rate of the reaction. The main product, 2-(4-(2-hydroxy-3-oxopropoxy)phenyl)acetamide, was identified with the aid of IR and mass spectral data. Stoichiometry with respect to the drug substrate and reagent was established as 2:1. Added H 2 SO 4 , SO 4  2−  and HSO 4  −  showed negligible effect on the rate of the reaction. HCe(SO 4 ) 3  −  was found to be the predominant reactive species under the specified experimental conditions. The rate constants ( k ), catalytic constant ( k c  ) and equilibrium constant ( K  6 ) for the proposed mechanism were determined. The kinetic and thermodynamic activation parameters were computed for both the slow rate determining step and complex forming equilibrium step.

zeitschrift für physikalische chemie

Mn(II) Catalyzed Oxidation of Atenolol by Cerium(IV) in Aqueous Sulfuric Acid Medium: A Spectrophotometer Aided Kinetic, Mechanistic and Thermodynamic Study