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Two compounds, compounds  1  and  2 , were isolated from  Preussia  sp. The molecular structures of both compounds were elucidated by analyzing one-dimensional (1D) and 2D nuclear magnetic resonance data along with high-resolution mass spectrometry data. Compound  1  was obtained as novel in structure, and compound  2  was recently reported elsewhere. Compound  1  did not show antioxidant and antimicrobial activities and brine shrimp toxicity, while compound  2  showed strong antioxidant activity (DPPH reduction capacity; IC 50 =3 μg/mL) and brine shrimp toxicity (LD 50 =50 μg/mL).

Antimicrobial and antioxidant activities of two polyketides from lichen-endophytic fungus Preussia sp.