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Phytochemical investigation of the semi-parasitic plant,  Plicosepalus curviflorus  (Loranthaceae) growing in Saudi Arabia resulted in the isolation of a new catechin–gallic acid derivative of inositol, plicosepalin A ( 1 ) [(+) catechin-4′- O -(1″- O -galloyl-5″- O -methyl)- myo -inositol], along with seven known compounds: methyl gallate ( 2 ), catechin ( 3 ), quercetin ( 4 ), gallic acid ( 5 ), lupeol ( 6 ), β-sitosterol ( 7 ), and ursolic acid ( 8 ). Their structures were elucidated on the basis of spectroscopic analyses, including HRESIMS, ESIMS,  1 H and  13 C NMR, HSQC, and HMBC, as well as comparison with reported data. The antioxidant and antimicrobial activities of  1  were evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and the disc diffusion assay, respectively. Compound  1  exhibited potent free radical scavenging activity with an IC 50  value of 9.0 ± 0.27 μM. Moreover, significant activities against  Staphylococcus aureus  and  Bacillus subtilis  were recorded.

Plicosepalin A, a new antioxidant catechin–gallic acid derivative of inositol from the mistletoe Plicosepalus curviflorus