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The triterpenes friedelin ( 1 ), β-friedelinol ( 2 ) and 3,15-dioxo-21α-hydroxyfriedelane ( 3 ) in the aerial parts of  Maytenus robusta , a Brazilian medicinal plant with antiulcer potential, were seasonally quantified by gas chromatography flame-ionization detection (GC-FID) using an external standard. The method was found to be linear, precise and sensitive. Compounds  1  and  2  were found in  M. robusta  leaves and branches, with highest concentrations in the leaves collected in autumn, i.e. 3.21 ± 0.16 and 12.60 ± 1.49 mg g −1  dry weight of  1  and  2 , respectively. On the other hand, compound  3  was found only in the branches, with the highest concentrations in winter and autumn (0.21 ± 0.01 and 0.20 ± 0.02 mg g −1 ). The results allow to define the optimal season and plant parts for the collection of  M. robusta  as a phytotherapeutic drug.

zeitschrift für naturforschung c

Seasonal variation of gastroprotective terpenoids in  Maytenus robusta  (Celastraceae) quantified by gas chromatography-flame ionization detection (GC-FID)