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The new cyclic heptapeptide unguisin F ( 1 ) and the known congener unguisin E ( 2 ), were obtained from the endophytic fungus  Mucor irregularis , isolated from the medicinal plant  Moringa stenopetala , collected in Cameroon. The structure of the new compound was unambiguously determined on the basis of one- and two-dimensional NMR spectroscopy as well as by high-resolution mass spectrometry. The absolute configuration of the amino acid residues of  1  and  2  was determined using Marfey’s analysis. Compounds  1  and  2  were evaluated for their antibacterial and antifungal potential, but failed to display significant activities.

Unguisin F, a new cyclic peptide from the endophytic fungus Mucor irregularis