English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The aim of the present work was to investigate the Schistosoma mansoni and Fasciola gigantica cross-reactivity between adult worms and egg homogenates of the parasites. Immunoprophylactic effects of crude Schistosoma mansoni worms and egg antigens mixed with or without saponins extracted from Atriplex nummularia were studied followed by challenge with 80 cercariae of Schistosoma mansoni. Our results showed that post 1st immunization with schistosome egg antigens (SEA) there was a significant change (P ≈ 0.05) in the IgM levels against Fasciola egg homogenate (FgEH) without saponins. Post 2 nd  immunization with SEA mixed with saponins the levels of IgM increased significantly (P ≈ 0.05) against Fasciola worm homogenate (FgWH) as compared with a non-immunized group. Post 2 nd  immunization the level of IgG was significantly elevated (P ≈ 0.05) by SEA mixed with saponins against FgWH. Post 2 nd  immunizations with SEA mixed with saponins showed a signifi cant change (P ≈ 0.05) in IgG levels against FgEH. These results clearly demonstrated that there is a cross-reactivity between Schistosoma mansoni eggs and Fasciola gigantica worms and eggs. Saponins were found to be immunostimulatory adjuvants in our study

Cross-Reactivity of Schistosoma mansoni-Fasciola gigantica Influenced by Saponins