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In a double-logarithmic plot of the rate of actin polymerization against monomer concentration, the slope has a lower value in the presence of the fungal metabolites cytochalasin B and D than in their absence. This suggests that actin oligomers which serve as polymerization nuclei are smaller in the presence of cytochalasins than in their absence.

Evidence that Cytochalasins Reduce the Size of Polymerization Nuclei during Actin Polymerization