English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Bleaching herbicides inhibit carotene biosynthesis in photosynthetic organisms. The interaction of norflurazon [4-chloro-5-methylamino-2-(3-trifluoromethylphenyl)-pyridazin-3(2H)one] with its target enzyme phytoene desaturase, has been characterized by enzyme-kinetic studies. A Lineweaver-Burk plot showed a non-competitive m anner for norflurazon inhibition. Binding of norflurazon to phytoene desaturase was reversible as dem onstrated by complete replacem ent of bound  14 C-labeled herbicide by unlabeled norflurazon. In a linear Dixon plot the k i  value for norflurazon was determ ined as 0.09 μм . With the in vitro system from Anacystis used in this study it was possible to perform structure-activity studies with selected m -phenyl-substituted pyridazinones. A linear relationship between inhibitory properties of these compounds and their lipophilicity could be established.

Enzyme-Kinetic Studies on the Interaction of Norflurazon with Phytoene Desaturase