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The irritant and tumor-promoting constituents of latex of Euphorbia urucalli L. originating from South Africa were isolated. They were identified as irritant ingenane and tiglianc type diterpene esters derived from unsaturated aliphatic acids and acetic acid and the polyfunctional diterpene parent alcohols 4-deoxyphorbol, phorbol and ingenol, respectively.

zeitschrift für naturforschung c

On the Active Principles of the Spurge Family (Euphorbiaceae) XI. [1] The Skin Irritant and Tumor Promoting Diterpene Esters of Euphorbia tirucalli L. Originating from South Africa