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Whether proteins or nucleic acids were responsible for the emergence of life has been debated for a long time. Taking the observation that families of proteins display a remarkable invariance of their amino acid sequence around critical regions, such as active/binding sites, even though these proteins may represent considerable evolutionary diversity, as the naturally provided evidence of evolutionary selection of a working system, the idea is developed that:

Origins of the First Cell. A New Model for the Spontaneous Formation of the First Living Cell Based on a Novel Approach