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s 107 LH-RH can also be assayed in urine. 1 — 2 percent of an injected dose is excreted within 8 hours. Basal excretion rates in normal human subjects are 15 — 60 ng/day. Urine LH-RH is immunochemically iden­ tical but chromatographically (on ion-exchange columns) different and evidence sugests that it is the des-glu1-nonapeptide or des-glu1, his2-octapeptide of LH-RH. LH-RH has been detected and measured by radio­ immunoassay in the blood of rats, rabbits, chickens, LH-RH in Paediatrics

Identification and Measurement of LH-RH in Biological Fluids by Radioimmunoassay