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Embryonic rat cells are stopped in G 1 -phase when they are incubated in serum-free medium. They can be triggered to proceed through their cell cycle by the addition of two proteins which have been isolated from fetal calf serum. The influence of calcium and potassium ions on the stimulation process has been exam ined:

zeitschrift für naturforschung c

VI. Calcium- und Kaliumionen als Cofaktoren: Stimulierung von Kulturen embryonaler Rattenzellen durch Kälberserum / VI. Calcium and Potassium Ions as Cofactors