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An efficient synthesis of hexahydro-4-phenylquinoline-3-carbonitriles is described by the four-component condensation reaction of cyclohexanone, ammonium acetate, malononitrile, and aromatic aldehydes using Fe 3 O 4 @SiO 2 -SO 3 H nanoparticles as a superior and retrievable heterogeneous catalyst under ultrasonic irradiations. The reusability of the catalyst and little catalyst loading, excellent yields, short reaction times, using the sonochemical procedure as a green process and an alternative energy source are some benefits of this method.

zeitschrift für naturforschung b

Synthesis of hexahydro-4-phenylquinoline-3-carbonitriles using Fe 3 O 4 @SiO 2 -SO 3 H nanoparticles as a superior and retrievable heterogeneous catalyst under ultrasonic irradiations