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In continuation of our search for new secondary metabolites from African Erythrina species, E. mildbraedii of Cameroon was investigated. As a result of this study, a new flavanone (mildbone, 1) and a new chalcone (mildbenone, 2) have been obtained and characterized by spectroscopic means. Both the compounds exhibited significant antioxidant and moderate lipoxygenase inhibitory activities. Compounds 1 and 2 showed potent antioxidant activity even stronger than the positive control. Among both the compounds, mildbone (1) was found to be potent in both the assays.

Potent Antioxidant and Lipoxygenase Inhibitory Flavanone and Chalcone from Erythrina mildbraedii Harms (Fabaceae) of Cameroon