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For optimal growth of embryonic rat cells in tissue culture the amino acid serine is essential. It can be substituted by equimolar amounts of glyoxylic acid; radioactivity from 1- 14 C-glyoxylic acid is incorporated into various amino acids among which serine is also found. The presented experiments show that there must be a deficiency of C 2 -fragments in the metabolism of embryonic rat cells.

zeitschrift für naturforschung b

Mangel an C 2 -Fragmenten im Intermediärstoffwechsel embryonaler Rattenzellen in Kultur / Deficiency of C 2 -Fragments in the Metabolism of Embryonic Rat Cells in Culture