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With the aid of isotopic techniques the ribonucleic acid (RNA) and protein metabolism of embryonic chicken cells infected with fowl plague virus was studied. In addition to normal cell-RNA only viral RNA was found in the infected cells. The synthesis starts after 1 hour p.i. and proceeds during the rest of the infectious cycle. By labelling the viral subunits (s-antigen and hemagglutinin) with  14 C-leucine it could be demonstrated, that the synthesis of their protein components starts also at about 1 hour post infectionem.

zeitschrift für naturforschung b

Zusammenhänge zwischen der Synthese von Ribonucleinsäure und Protein bei der Vermehrung eines Virus der Influenza-Gruppe (Virus der Klassischen Geflügelpest)