English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background Various studies have reported different results for cortisol, dehydroepiandrosterone sulfate (DHEA-S) and 25-hydroxyvitamin D (25(OH)D) levels in patients with chronic spontaneous urticaria (CSU) and these were not sufficient for explaining the underlying reasons. Objectives To evaluate the levels of cortisol, DHEA-S and 25(OH)D in patients with CSU and to investigate the relationships between these parameters. Methods Fifty patients who had diagnosed with CSU and 30 healthy controls were enrolled into the study. Stress levels of CSU and control groups were determined by perceived stress scale (PSS-14). The activity of urticaria of the patients was also determined by urticaria activity score (UAS7). Serum DHEA-S, cortisol and 25(OH)D levels of the participants were measured and compared. Results DHEA-S and 25(OH)D levels of CSU patients were lower than the control group (p&lt;0.001 and p&lt;0.001, respectively) while stress level and cortisol/DHEA-S ratio were higher (p&lt;0.001 and p=0.003, respectively). Conclusions Lower 25(OH)D levels and higher cortisol/DHEA-S ratio in CSU patients who have higher stress level indicate that the level of 25(OH)D seems to be associated with steroidogenesis and thus 25(OH)D levels may decrease secondarily in CSU.

Evaluation of serum 25-hydroxyvitamin D levels and cortisol/dehydroepiandrosterone sulfate ratio in chronic spontaneous urticaria