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This paper develops a new estimator for cointegrating and spurious regressions by applying a two-stage generalized Cochrane-Orcutt transformation based on an autoregressive approximation framework, even though the exact form of the error term is unknown in practice. We prove that our estimator is consistent for a wide class of regressions. We further show that a convergent usual  t -statistic based on our new estimator can be constructed for the spurious regression cases analyzed by (Granger, C. W. J., and P. Newbold. 1974. “Spurious Regressions in Econometrics.”  Journal of Econometrics  74: 111–120) and (Granger, C. W. J., N. Hyung, and H. Jeon. 2001. “Spurious Regressions with Stationary Series.”  Applied Economics  33: 899–904). The implementation of our estimator is easy since it does not necessitate estimation of the long-run variance. Simulation results indicate the good statistical properties of the new estimator in small and medium samples, and also consider a more general framework including multiple regressors and endogeneity.

A simple solution of the spurious regression problem