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Currently available treatments for neuropathic pain fail in roughly half of the patients – and it is impossible to predict which treatments will help patients. Stratification of neuropathic pain patients is needed, and sensory profiling has so far been the most promising approach: it has been shown to be responsive to treatment, linked to potential mechanisms, and, most importantly, predictive of treatment success. Despite a number of limitations, it is the currently most promising stratification tool and should be refined rather than disregarded.

Sensory testing might not be perfect – but it is the best biomarker for pain phenotypes we have right now