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The potential for production of the medically relevant  64 Cu has been investigated by proton irradiation of highly enriched  67 Zn targets. The excitation function of the  67 Zn( p ,  α ) 64 Cu a nuclear reaction was measured by the stacked-foil technique up to 30 MeV. The prediction of the TALYS code was also compared to the measured cross section results. Based on the improved database of the  67 Zn( p ,  α ) 64 Cu reaction, thick target yield as a function of energy was also deduced. Production possibility of  64 Cu is discussed in detail, employing different energy proton beams and with regards to the  61 Cu and  67 Cu contamination levels as a function of the target enrichment level. By using 1  μ A beam intensity, 6.3505 h irradiation time and enriched  67 Zn target ( 64 Zn ≤ 0.5%,  66 Zn ≤ 9%,  67 Zn ≥ 80%,  68 Zn ≤ 10% and  70 Zn ≤ 0.5%), the expected EOB (End Of bombardment) yields are 43.66, 88.80 and 156.14 MBq/ μ A at 12, 15 and 18 MeV proton energies, respectively. Application time-frames were also deduced where the total radio-copper contamination level remains below 1%.

Excitation function of ( p , α ) nuclear reaction on enriched 67 Zn: possibility of production of 64 Cu at low energy cyclotron