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In this study, the role of process systems engineering in enhancing the algae economy is highlighted. First, basic characteristics of the various strains of microalgae are presented. In addition, the beneficial extracted bioproducts and their applications are reviewed. Then, an overview of the various technologies available in each step of biorefinery to produce added-value products and biofuels from microalgae is provided. These technologies are compared in terms of required energy and efficiency. Different perspectives of the algae industry, from molecule to enterprises scale where process systems engineering can have a role, are addressed. Subsequently, the roles of process systems engineering in process and product design, process control, and supply chain of the algae biorefinery are discussed. It is found that process systems engineering can play an important role in the biobased economy, especially by applying sustainability and economic concepts in the decision-making process for selecting the best feedstock, processing pathways, and desired products. Tools such as market analysis, techno-economic analysis, life cycle assessment (LCA), and supply chain (SC) analysis can be applied to design sustainable algae biorefinery. There are, however, several challenges such as the lack of data, the complexity of optimization, and validation that should be addressed before using these tools.

The role of bioprocess systems engineering in extracting chemicals and energy from microalgae