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Making cryogels, which are among today’s accepted adsorbents, more functional with different methods, has been one of the subjects spent overtime. In this study, water-soluble poly(maleic anhydride- alt -acrylic acid) polymer embedded in poly(2-hydroxyethyl methacrylate) cryogels. Copper ions were then immobilised to this structure, and this polymer was used for adsorption of haemoglobin from aqueous systems. Adsorption interaction was carried out on an electrostatic basis, and approximately 448.62 mg haemoglobin/g polymer adsorption capacity value was obtained. It was found that the same material has managed to maintain its adsorption ability by 90.3% even after the use of it five times in the adsorption/desorption cycle. The adsorption interaction was determined to be appropriate for the Langmuir model by isotherm studies. The change in Gibbs free energy value was calculated as −2.168 kJ/mol.

Water-soluble polymeric particle embedded cryogels: Synthesis, characterisation and adsorption of haemoglobin