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The ongoing SARS-CoV-2 pandemic has triggered several months of global turmoil, and governments across the world are now actively attempting to develop strategies to combat both the virus and its societal impact. Since SARS-CoV-2 is a novel pathogen, basic research is essential, and manifold international efforts are now underway in order to elucidate the molecular mechanisms of both the SARS-CoV-2 infection process and the resulting disease, COVID-19. In this article we discuss how the field of Human Genetics can contribute to this endeavor, and summarize available findings from human genetic COVID-19 research. Finally, we briefly outline how through the use of existing national research infrastructure, German scientists can facilitate progress in this novel and fast-moving field.

Combating the SARS-CoV-2 pandemic: How can the field of Human Genetics contribute?