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Study on calculation model and risk area of radionuclide diffusion in coastal waters under nuclear leakage accidents with different levels can help predict and evaluate consequences of radionuclide leakage accidents. Thus they play an important role in emergency response and accident mitigation. In the first step of the study, a climate hydrodynamic model in China coastal waters was established based on the climate data. In the next step, according to the real-time meteorological data, a hydrodynamic model in coastal waters of Haiyang nuclear power station was founded using the result of the climate hydrodynamic as a boundary. Then, according to the result of the hydrodynamic model in coastal waters of Haiyang nuclear power station, a radionuclide diffusion model in coastal waters of Haiyang nuclear power station was set up, in which the Euler method was adopted. With the radionuclide diffusion model, the total leaked radioactivity of radionuclides was set from 10 18  Bq to 10 12  Bq with a decrease of every two orders of magnitude. Thus, scenarios of radionuclide diffusion under assumed nuclear leakage accidents with different levels were calculated and their corresponding risk area were analyzed under the assumption that radionuclides leaked for consecutive five days. The results show that when the leaked radioactivity of radionuclides is 10 18  Bq, the risk area on the seventh day is about 41 km east, 22 km south and 19 km west of the power station; on the fourteenth day, the risk area is about 65 km east, 22 km south and 25 km west of the power station. When the total leaked radioactivity of radionuclides declines by two orders of magnitude, the risk area will be reduced by about 10 km–20 km in the east direction accordingly. When it declines to 10 14  Bq, the risk area decreases sharply to a small area. When it declines to 10 12  Bq, the risk area is barely found. This model was verified from two aspects, namely the flow field and the radionuclide concentration. Hydrodynamic results can well describe the Yellow Sea cold water mass, Yellow Sea warm current and tidal current. Changes of radioactivity in different positions are fundamentally consistent with that in Fuikushima nuclear leakage accident. It indicates the hydrodynamic model and radionuclide diffusion model in the study are feasible and reliable.