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Objective:  The aim of this prospective study was to compare serum and urine concentrations of progesterone-induced blocking factor (PIBF) and serum concentrations of anti-inflammatory (IL10) and pro-inflammatory (IL6, TNFα, IFNγ) cytokines of women with threatened spontaneous abortion with normal pregnancy and to evaluate the impact of PIBF on outcome of pregnancy.

Progesterone – induced blocking factor (PIBF) and Th 1 /Th 2 cytokine in women with threatened spontaneous abortion