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Objective:  While an echogenic intracardiac focus (EIF) is associated with an increased risk of trisomy 21 (T21), the magnitude of that risk remains controversial, particularly in the setting of a low-risk triple screen (TS). The objective of this study is to define the risk of T21 in patients with a low-risk TS and an isolated EIF.

Isolated echogenic intracardiac foci in patients with low-risk triple screen results: assessing the risk of Trisomy 21