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Objective:  To assess the sensitivity (Sen) and false positive ratio (FPR) of stepwise sequential screening [1 st  step: combined test (CT), 2 nd  step: modified genetic sonography (major malformation and nuchal fold, MGS)] as a screening method for Down’s syndrome (DS) in the general population of pregnant women.

journal of perinatal medicine

Stepwise sequential screening for Down’s syndrome (combined test associated with modified genetic sonography) in pregnant women with low risk for chromosomal disorders