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Exercise affects growth and development through a complex interaction between the endocrine, immune, and nervous systems. To date very little is known about how these systems respond to exercise in children or adolescents. Moreover, there are few studies that have examined growth factors, pro-inflammatory cytokines, and peripheral blood mononuclear cell responses to 'real-life' or field exercise solely in girls.

Immunological and Growth Mediator Response to Cross-Country Training in Adolescent Females