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In addition to its growth promoting properties, growth hormone (GH) has anti-insulin effects that could cause hyperglycemia. Development of diabetes mellitus as a result of GH therapy has been an ever-present, albeit rarely reported, concern. This report is that of two adolescent boys who developed diabetes mellitus after the initiation of treatment with GH.

Development of Diabetes Mellitus in Two Boys After the Initiation of Growth Hormone Therapy