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Girls with central precocious puberty (CPP) are treated with gonadotropin releasing hormone (GnRH) analogues to suppress puberty. Gonadotropin levels are used to monitor treatment, since estradiol is difficult to measure at low levels. The optimal degree of hormonal suppression is still unknown.

journal of pediatric endocrinology and metabolism

Luteinizing Hormone (LH) and Estradiol Suppression and Growth in Girls with Central Precocious Puberty: Is more suppression better? Are Pre-injection LH Levels Useful in Monitoring Treatment?