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Normalization of plasma thyrotropin in T4-supplemented patients with thyroidal congenital hypothyroidism (CH) requires elevated plasma FT4-concentrations compared to patients with acquired thyroidal hypothyroidism. We investigated bone mineral density (BMD) in patients with CH.

The Effect of Life-long Thyroxine Treatment and Physical Activity on Bone Mineral Density in Young Adult Women with Congenital Hypothyroidism