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Neonatal diabetes mellitus (NDM) is a rare monogenic diabetes form, occurring mainly from ATP-binding cassette subfamily C member 8 ( ABCC8 ) and KCNJ11 mutations. ABCC8 mutations have also been found to cause adult-onset diabetes. What is new?: •Novel ABCC8 mutation in an NDM case •Heterogeneous clinical presentation of diabetes and response to sulfonylurea therapy among family members with the same ABCC8 mutation.

journal of pediatric endocrinology and metabolism

Transient neonatal diabetes due to a disease causing novel variant in the ATP-binding cassette subfamily C member 8 ( ABCC8 ) gene unmasks maturity-onset diabetes of the young (MODY) diabetes cases within a family