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Background:  Oral levothyroxine (L-T4) supplementation is usually an effective therapy in pediatric hypothyroidism, except in patients with malabsorption or pseudomalabsorption. In these cases, parenteral L-T4 may be required, but there is a paucity of information about this delivery method in the pediatric population.

More than one way to skin a thyroid. Managing pediatric hypothyroidism with weekly intramuscular levothyroxine