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Background and aims:  The allele variant of neurokinin B and its receptor genes were thought important in regulating the human reproductive axis in many populations. The aim of this study was to investigate whether the variances in  TAC3  and  TACR3  genes that encoded neurokinin B (NKB) and its receptor (NK3R), individually, were associated with idiopathic precocious puberty in Chinese girls.

Association study of TAC 3 and TACR 3 gene polymorphisms with idiopathic precocious puberty in Chinese girls