Additive interactions between retigabine and oxcarbazepine in the chimney test and the model of generalized tonic-clonic seizures in mice
Author(s) -
Zagaja Mirosław,
Barbara Miziak,
Katarzyna Załuska-Ogryzek,
Paweł Marzęda,
Drop Bartłomiej,
Załuska-Patel Karolina,
Ossowska Grażyna,
Stanisław J. Czuczwar,
Jarogniew J. Łuszczki
Publication year - 2016
Publication title -
journal of epileptology
Language(s) - English
Resource type - Journals
eISSN - 2300-0147
pISSN - 2299-9728
DOI - 10.1515/joepi-2016-0016
Subject(s) - oxcarbazepine , pharmacology , medicine , modafinil , epilepsy , pharmacodynamics , anticonvulsant , anesthesia , carbamazepine , pharmacokinetics , psychiatry
. Patients with pharmacoresistant epilepsy are usually treated with two or more antiepileptic drugs (AEDs). The search for therapeutically efficacious AED combinations is still a challenging issue for clinicians and epileptologists throughout the world
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