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Mandatory are short periods of sample storage, including transport time. Generally, 2 to a maximum of 4 h is a prerequisite for microbiological rapid diagnostics of acceptable quality (s. all Microbiological – Infectiological Quality Standards – MIQ). This requirement is 1) to prevent overlooking potentially pathogenic microorganisms by extended storage times resulting in their death after 2 h, or overgrowth by colonisation of other bacteria or fungi, 2) to avoid economic losses, e.g., because of the combination with the German Diagnostic Related Group (G-DRG) with short times of stay in the hospital or to achieve so-called complication points by detecting resistant microorganisms in time and therefore optimising reimbursement, 3) to fulfil the demand for a specific therapy aimed at the causative infectious agent which may not be detected after a longer storage time and to avoid higher mortality rates by failure or delayed times of specific therapy because of delayed isolation of resistant bacteria.

journal of laboratory medicine

The significance of specimen storage and transport for a quick microbiologic diagnosis under consideration of economic issues and the interests of patients  2