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Since bacterial infection of the recipient has become the most frequent infection risk in transfusion medicine, suitable methods for bacteria detection in blood components are of great interest. Platelet concentrates are currently in the focus of attention as they are stored under temperature conditions, which enable the multiplication of most bacteria species contaminating blood donations. Rapid methods for bacteria detection allow testing immediately before transfusion in a bedside-like manner. This approach would overcome the sampling error observed in early sampling combined with culturing of bacteria and would at least prevent the transfusion of highly contaminated blood components leading to acute septic shock or even death of the patient.

Improvement of bacteria detection by flow cytometry (BDFC) / Verbesserter Nachweis von Bakterien mittels Durchflusszytometrie