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Venous thromboembolism (VTE) tends to recur after oral anticoagulant therapy (OAT) withdrawal, regardless of the duration of treatment. As a result, the optimal duration of OAT after VTE is still a matter of debate. Patients are currently stratified in risk categories for recurrence on the basis of the clinical characteristics of the index event. Distal deep vein thrombosis (DVT) or VTE due to a transient risk factor are associated with a low risk of recurrence and a brief three-month course of anticoagulation is usually recommended. An event which is either idiopathic or with known thrombophilic defects, such as FV Leiden or the G20120A prothrombin mutation, is associated with a high risk of recurrence and an OAT course of at least six months is recommended.

laboratoriumsmedizin

The new role of D-dimer as a predictor of recurrent venous thromboembolism D-Dimere: Ihre neue Rolle als Prädiktoren für rezidivierende venöse Thromboembolien