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Both naturally occurring disease and man-made outbreaks remain serious biological threats. In order to address these threats, the United States has developed a framework of biopreparedness that includes several bioresponse capabilities, one of which is medical countermeasures. No one in the fields of public health or biodefense would be surprised by the fact that the United States is unprepared to respond to a virus for which no medical countermeasures exist. Additionally, bioweapons made resistant to US medical countermeasures would also be catastrophic. This paper describes the biothreats to the United States today, the development of US biopreparedness, the weaknesses of medical countermeasure capabilities, and recommendations on how to improve this area of biopreparedness.

The United States Medical Countermeasure Enterprise: A Broken Link in US Biopreparedness