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In response to the President's request of November 24, 2010, the Presidential Commission for the Study of Bioethical Issues (Bioethics Commission) oversaw a thorough review of current regulations and international standards to assess whether they adequately protect human participants in federally funded research, no matter where it occurs. The Bioethics Commission held four multi-day, public meetings. Speakers addressed a range of U.S. and international policies and norms, and provided perspectives from a wide array of professional and institutional organizations. At the President's request, the Bioethics Commission sought the advice of international experts and appointed the International Research Panel as a subcommittee. Finally, the Bioethics Commission solicited information from the public and it received over three hundred comments. The Bioethics Commission concluded that current regulations, which apply to a diverse and wide-ranging portfolio of research, generally appear to protect people from avoidable harm or unethical treatment. However, because of the currently limited ability of some governmental agencies to identify basic information about all of their human subjects research, the Bioethics Commission could not say that all federally funded research provides optimal protections against avoidable harms and unethical treatment. Many of our most important advances derive from research that involves human participants. It is essential, therefore, that critical research of this sort adheres to the highest ethical practices to ensure, as best as possible, that those who volunteer to participate in studies for the benefit of others are protected. Thus, the Bioethics Commission offered 14 recommendations to improve the current system.

Moral Science. Protecting Participants in Human Subjects Research: Presidential Commission for the Study of Bioethical Issues, USA