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The main function of myenteric neurons is the control of gut motility. As we recently showed that nitroxyl (HNO) induces intestinal smooth muscle relaxation, it was of interest to evaluate the effects of this signalling molecule on myenteric neurons in order to distinguish its properties in regard to myocytes.

Effects of the gaseous signalling molecule nitroxyl (HNO) on myenteric neurons governing intestinal motility