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Background:  Mounting experimental evidence highlights the testicular and neuronal toxicity of environmental/industrial chemicals in experimental animals via the mechanism involving oxidative damage. Nigerian Bonny Light crude oil (BLCO) has been reported to exhibit reproductive and neuronal toxicity in male rats. Studies have shown that vitamin E and quercetin protect rat neuronal and testicular cells from environmental chemical-induced oxidative damage. We investigated the possible protective role of quercetin and vitamin E in BLCO induced-neuronal and testicular toxicity.

Influence of vitamin E and quercetin on Nigerian Bonny Light crude oil-induced neuronal and testicular toxicity in Wistar rats