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Background:  Glucocorticoids (GCs) exert a wide range of anti-inflammatory, immunosuppressive, and antineoplastic activities. The aim of our investigation was to elucidate the effect of dexamethasone, a synthetic GC, on polyamine metabolism in the rat thymus.

Dexamethasone decreases the spermidine and spermine concentrations and polyamine oxidase activity in rat thymus