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Indoloquinolines were first synthesized as large flat molecules analogous to amodiaquine which showed superior antimalarial activity^ through the more effective inter-celative binding to DNA and RNA, and antitumor activity (1-6). As an extension of this work, we have synthesized some indoquinolines and indolobenzazepines from which we found that 3-chloro-9dimethylaminomethyl-8-methoxy[l l//]-indolo(3,2-c)quinoline showed useful antitumor activity (7).These promising results drove me to synthesize some other derivatives for lower toxicity and higher activity. Results and Discussion: In this work I would like to introduce four new indolo-quinolines namely; 3-methoxy or methyl-8-methoxy-9-diethyl or dimethylaminomethyl-[l 1 //]-indolo(3,2-c)quinolines la-d and four indolobenzazepines namely 3-methoxy or methyl-6,7-dihydro-9-methoxy-10-diethyl or dimethyl-aminomethylindolo(3,2-i/)-l-benzazepines 2a-d.

SYNTHESIS OF SOME INDOLO[3,2-c]QUINOLINES AND [3,2-d]BENZAZEPINES