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With an intention to synergize the antimicrobial activity of 1,3-diphenyl pyrazole and chromene derivatives, 20 hybrid compounds were synthesized and evaluated for their antimicrobial activity. Structures of the newly synthesized compounds were established by elemental analysis and spectral data. All compounds were evaluated for their antimicrobial activity against Gram positive and Gram negative bacteria and antifungal activity by a well diffusion method. Compounds  8 ,  10 ,  16  and  21  show reasonable antibacterial and antifungal activity.

Synthesis and evaluation of chromene-based compounds containing pyrazole moiety as antimicrobial agents