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Boronic acids play an important role in the design and synthesis of chemosensors for carbohydrates due to their ability to reversibly bind with diol-containing compounds. In this regard, the availability of boronic acids that change fluorescence upon sugar binding is crucial for a successful sensor design endeavor. Herein, we report two boronic acids that show strong fluorescent intensity changes upon sugar binding: isoquinoline-7-boronic acid (7-IQBA) and phenoxathiin-4-boronic acid (4-POBA).

Arylboronic acids with strong fluorescence intensity changes upon sugar binding