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An efficient one-pot synthesis of polyhydroacridines and polyhydroquinolines through the Hantzsch reaction in deep eutectic solvent choline chloride/urea (1:2) has been developed. Good to excellent yields, broad substrate compatibility as well as the reusability of the solvent are the major advantages of the present protocol.

Facile and green synthesis of Hantzsch derivatives in deep eutectic solvent