English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The main objective of the present investigation was to screen P. aeruginosa toxins for in vitro activity and investigate biochemical mode of action. Toxins were isolated after concentration of the culture filtrate and separation of the filtrate on Sephadex G-100 column in four fractions. On the basis of primary screening results the dialysate and fractions 3 and 4 effectively inhibited incorporation of [14C]adenine (DNA, RNA) and [14C]valine (protein) into the TCA-insoluble fraction of both Ehrlich ascites carcinoma (EAC) and Vero cells. The toxins also interfered with energy-yielding processes (endogenous respiration). The dialysate decreased the level of ATP in EAC cells after two hours incubation in vitro.

Pseudomonas aeruginosa Toxins: Effect on Ehrlich Carcinoma and Vero Cells in vitro